Hufbauer says there is “no doubt” that the United States “would have done better under the Trans-Pacific Partnership” than in the case of a bilateral agreement with Japan. “Trump is completely wrong that the TPP was a disaster, and I think he`s quite wrong to think that with this bilateral approach he`ll get a better deal – but he`s going to ask for a lot more. It may lead some countries to come up with his question – but we will see how far he goes. On the other hand, Hufbauer adds, “The great advantage of bilateral pacts from Trump`s point of view is that the United States, as a big boy on the block, will be able to extract more from its bilateral partners than its multilateral partners…. That`s the balance [Trump] is playing. Proponents of the Trans-Pacific Partnership had argued that one of the greatest virtues of the 12-country trade agreement was to open Japanese markets to U.S. exports, in a way that Japan only wanted to tolerate because the TPP also promised to improve market access for Japanese exporters in other TPP member countries in Asia and Latin America. Is it possible to negotiate a bilateral pact with Japan that would provide the United States with the same value – or better – that the TPP would have provided? “That`s the problem,” Guillen says. “Do these [bilateral] agreements open markets? It seems that the approach is ad hoc, on a case-by-case basis, and not holistic. The fourth drawback is that of small businesses in a country. A multilateral agreement gives a competitive advantage to large multinationals. They are already familiar with the operation in a global environment.
As a result, small businesses cannot compete. They lay off workers to reduce costs. Others relocate their factories to countries where living standards are lower. If a region depended on this industry, it would have high unemployment rates. This makes multilateral agreements unpopular. A trade agreement signed between more than two parties (usually neighbouring or in the same region) is considered multilateral. They face the main obstacles – to content negotiation and implementation. The more countries involved, the more difficult it is to achieve mutual satisfaction. Once this type of trade agreement is governed, it will become a very powerful agreement. The larger the GDP of the signatories, the greater the impact on other global trade relations.
The largest multilateral trade agreement is the North American Free Trade Agreement between the United States, Canada and Mexico.  The Asia-Pacific region “is an important market for our businesses,” says Rob Mulligan, senior vice president of policy and government affairs at the United States Council for International Business.